Gas‐source molecular‐beam epitaxy using Si2H6 and GeH4 and x‐ray characterization of Si1−xGex (0≤x≤0.33) alloys

Gas‐source molecular‐beam epitaxy (MBE) has been used to grow SiGe alloys with Si2H6 and GeH4 as sources on (100) Si substrates. Single‐crystalline epilayers with Ge composition as high as 33% have been produced at 610 °C, the lowest temperature hitherto used for gas‐source SiGe MBE. Growth parameters, growth modes, and the structural characteristics have been studied by a variety of in situ and ex situ techniques. Double‐crystal x‐ray diffraction data for the alloys have been obtained for the first time in thin mismatched layers.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69862/2/JAPIAU-71-10-4916-1.pd

The Intracluster Light and its Link with the Dynamical State of the Host Group/Cluster: the Role of the Halo Concentration

We investigate on the role of the halo concentration in the formation of the intra-cluster light (ICL) in galaxy groups and clusters, as predicted by a state-of-art semi-analytic model of galaxy formation, coupled with a set of high-resolution dark matter only simulations. The analysis focuses on how the fraction of ICL correlates with halo mass, concentration and fraction of early-type galaxies (ETGs) in a large sample of groups and clusters with $13.0\leq \log M_{halo} \leq 15.0$. The fraction of ICL follows a normal distribution, a consequence of the stochastic nature of the physical processes responsible for the formation of the diffuse light. The fractional budget of ICL depends on both halo mass (very weakly) until group scales, and concentration (remarkably). More interestingly, the ICL fraction is higher in more concentrated objects, a result of the stronger tidal forces acting in the innermost regions of the haloes where the concentration is the quantity playing the most relevant role. Our model predictions do not show any dependence between the ICL and ETGs fractions and so, we instead suggest the concentration rather than the mass, as recently claimed, to be the main driver of the ICL formation. The diffuse light starts to form in groups via stellar stripping and mergers and later assembled in more massive objects. However, the formation and assembly keep going on group/cluster scales at lower redshift through the same processes, mainly via stellar stripping in the vicinity of the central regions where tidal forces are stronger.Comment: 16 pages, 6 figures, 1 table. Accepted for publication in ApJ, small correction

The Impact of Futures Trading on Cash Market Volatility: Evidence from the Tokyo Stock Exchange

This paper has examined Japanese stock market volatility using alternative estimates of volatility and several testing procedures to compare the time periods before and after the introduction of index futures contracts. On the basis of 100 randomly selected stocks, empirical evidence from these texts indicates that futures trading had an insignificant impact on prove volatility in the cash market. The results are generally consistent with what has been reported for the U.S. market

Array automated assembly task, phase 2. Low cost silicon solar array project

Several modifications instituted in the wafer surface preparation process served to significantly reduce the process cost to 1.55 cents per peak watt in 1975 cents. Performance verification tests of a laser scanning system showed a limited capability to detect hidden cracks or defects, but with potential equipment modifications this cost effective system could be rendered suitable for applications. Installation of electroless nickel plating system was completed along with an optimization of the wafer plating process. The solder coating and flux removal process verification test was completed. An optimum temperature range of 500-550 C was found to produce uniform solder coating with the restriction that a modified dipping procedure is utilized. Finally, the construction of the spray-on dopant equipment was completed

Multiform antimicrobial resistance from a metabolic mutation

A critical challenge for microbiology and medicine is how to cure infections by bacteria that survive antibiotic treatment by persistence or tolerance. Seeking mechanisms behind such high survival, we developed a forward-genetic method for efficient isolation of high24 survival mutants in any culturable bacterial species. We found that perturbation of an essential biosynthetic pathway (arginine biosynthesis) in a mycobacterium generated three distinct forms of resistance to diverse antibiotics, each mediated by induction of WhiB7— high persistence and tolerance to kanamycin, high survival upon exposure to rifampicin, and MIC-shifted resistance to clarithromycin. As little as one base change in a gene encoding a metabolic pathway component conferred multiple forms of resistance to multiple antibiotics with different targets. This extraordinary resilience may help explain how sub31 sterilizing exposure to one antibiotic in a regimen can induce resistance to others and invites development of drugs targeting the mediator of multiform resistance, WhiB7

Arts on prescription for community‐dwelling older people with a range of health and wellness needs

Published evidence for the role of participatory art in supporting health and well‐being is growing. The Arts on Prescription model is one vehicle by which participatory art can be delivered. Much of the focus of Arts on Prescription has been on the provision of creative activities for people with mental health needs. This Arts on Prescription program, however, targeted community‐dwelling older people with a wide range of health and wellness needs. Older people were referred to the program by their healthcare practitioner. Professional artists led courses in visual arts, photography, dance and movement, drama, singing, or music. Classes were held weekly for 8–10 weeks, with six to eight participants per class, and culminated with a showing of work or a performance. Program evaluation involved pre‐ and postcourse questionnaires, and focus groups and individual interviews. Evaluation data on 127 participants aged 65 years and older were available for analysis. We found that Arts on Prescription had a positive impact on participants. Quantitative findings revealed a statistically significant improvement in the Warwick–Edinburgh Mental Well‐being Scale(WEMWBS) as well as a statistically significant increase in the level of self‐reported creativity and frequency of creative activities. Qualitative findings indicated that the program provided challenging artistic activities which created a sense of purpose and direction, enabled personal growth and achievement, and empowered participants, in a setting which fostered the development of meaningful relationships with others. This evaluation adds to the evidence base in support of Arts on Prescription by expanding the application of the model to older people with a diverse range of health and wellness needs

Decentralised Learning MACs for Collision-free Access in WLANs

By combining the features of CSMA and TDMA, fully decentralised WLAN MAC schemes have recently been proposed that converge to collision-free schedules. In this paper we describe a MAC with optimal long-run throughput that is almost decentralised. We then design two \changed{schemes} that are practically realisable, decentralised approximations of this optimal scheme and operate with different amounts of sensing information. We achieve this by (1) introducing learning algorithms that can substantially speed up convergence to collision free operation; (2) developing a decentralised schedule length adaptation scheme that provides long-run fair (uniform) access to the medium while maintaining collision-free access for arbitrary numbers of stations

Sorting live stem cells based on Sox2 mRNA expression.

PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.While cell sorting usually relies on cell-surface protein markers, molecular beacons (MBs) offer the potential to sort cells based on the presence of any expressed mRNA and in principle could be extremely useful to sort rare cell populations from primary isolates. We show here how stem cells can be purified from mixed cell populations by sorting based on MBs. Specifically, we designed molecular beacons targeting Sox2, a well-known stem cell marker for murine embryonic (mES) and neural stem cells (NSC). One of our designed molecular beacons displayed an increase in fluorescence compared to a nonspecific molecular beacon both in vitro and in vivo when tested in mES and NSCs. We sorted Sox2-MB(+)SSEA1(+) cells from a mixed population of 4-day retinoic acid-treated mES cells and effectively isolated live undifferentiated stem cells. Additionally, Sox2-MB(+) cells isolated from primary mouse brains were sorted and generated neurospheres with higher efficiency than Sox2-MB(-) cells. These results demonstrate the utility of MBs for stem cell sorting in an mRNA-specific manner